Publications

Click on the articles below. More publications by Dr. Chapkin and the Chapkin Lab Team can be found on PubMed.

• Diet therapy abates mutant APC and KRas effects by reshaping plasma membrane cholesterol nanodomains
  December 22, 2024 by Eunjoo Kim
  Cholesterol-enriched plasma membrane domains are known to serve as signaling […]
• Graphical Dirichlet Process for Clustering Non-Exchangeable Grouped Data
  December 18, 2024 by Arhit Chakrabarti
  We consider the problem of clustering grouped data with possibly […]
• 1,4-dihydroxy-2-naphthoic acid prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced motor function deficits
  December 11, 2024 by Caitlin A Madison
  Parkinson's disease (PD), characterized by death of dopaminergic neurons in […]
• Involvement of Intestinal Epithelium Aryl Hydrocarbon Receptor Expression and 3, 3'-Diindolylmethane in Colonic Tertiary Lymphoid Tissue Formation
  September 28, 2024 by Erika L Garcia-Villatoro
  Tertiary lymphoid tissues (TLTs) are adaptive immune structures that develop […]
• TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) induces depression-like phenotype
  June 5, 2024 by Roanna A Debler
  The etiology of major depressive disorder (MDD) remains poorly understood. […]
• Integrated analysis of gut metabolome, microbiome, and exfoliome data in an equine model of intestinal injury
  April 15, 2024 by C M Whitfield-Cargile
  CONCLUSIONS: Results of integrative analysis identified an important role for […]
• Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response
  April 8, 2024 by Gioia Heravi
  Monounsaturated fatty acids (MUFAs) play a pivotal role in maintaining […]
• Aryl hydrocarbon receptor activity in intestinal epithelial cells in the formation of colonic tertiary lymphoid tissues
  April 2, 2024 by E L Garcia-Villatoro
  After birth, the development of secondary lymphoid tissues (SLTs) in […]
• A Unified Bayesian Framework for Bi-overlapping-Clustering Multi-omics Data via Sparse Matrix Factorization
  January 5, 2024 by Fangting Zhou
  The advances of modern sequencing techniques have generated an unprecedented […]
• Interfacial Electromigration for Analysis of Biofluid Lipids in Small Volumes
  December 5, 2023 by Madison E Edwards
  Lipids are important biomarkers within the field of disease diagnostics […]
• Bis-indole-derived NR4A1 antagonists inhibit colon tumor and splenic growth and T-cell exhaustion
  October 17, 2023 by Kumaravel Mohankumar
  There is evidence that the orphan nuclear receptor 4A1 (NR4A1, […]
• Fate and distribution of orally-ingested CeO₂-nanoparticles based on a mouse model: Implication for human health
  October 13, 2023 by Xingmao Ma
  The use of nanoparticles in agrichemical formula and food products […]
• Extinction scenarios in evolutionary processes: a multinomial Wright-Fisher approach
  September 26, 2023 by Alexander Roitershtein
  We study a discrete-time multi-type Wright-Fisher population process. The mean-field […]
• Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin
  July 19, 2023 by Alfredo Erazo-Oliveras
  Although the role of the Wnt pathway in colon carcinogenesis […]
• Gene knockout inference with variational graph autoencoder learning single-cell gene regulatory networks
  May 29, 2023 by Yongjian Yang
  In this paper, we introduce Gene Knockout Inference (GenKI), a […]