Click on the articles below. More publications by Dr. Chapkin and the Chapkin Lab Team can be found on PubMed.
- by Alfredo Erazo-OliverasAn effective therapeutic strategy to treat oncogenic Wnt signaling in the context of colorectal cancer (CRC) remains elusive. A new […]
- by Lei ZhangBis-indole-derived compounds including 1,1-bis(3'-indolyl)-1-(3,5-disubstitutedphenyl)methane (DIM-3,5) analogs bind both orphan nuclear receptors 4A1 (NR4A1) and NR4A2, and DIM-3,5 compounds act as […]
- by Michael L SalinasCONCLUSIONS: These findings suggest that human milk downregulates peripheral immune cell cytokine transcriptional signatures linked to allergic inflammation and infection […]
- by Ebru Ece GülşanGut microbial metabolism of dietary flavonoids leads to a diverse array of bioactive products that are closely associated with human […]
- by Gioia HeraviCONCLUSION: Our findings suggest that PUFA desaturation is crucial for rescuing cancer cells from persistent ER stress, supporting FADS1 as […]
- by Victoria GatlinSingle-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular variability by capturing gene expression profiles of individual cells. The […]
- by Amanuel HailemariamPolyfluoroalkyl substances (PFAS) are widely used industrial compounds that have been identified as contaminants in almost every component of the […]
- Diet therapy abates mutant APC and KRas effects by reshaping plasma membrane cholesterol nanodomainsby Eunjoo KimCholesterol-enriched plasma membrane domains are known to serve as signaling platforms in a diverse array of cellular processes. However, the […]
- by Arhit ChakrabartiWe consider the problem of clustering grouped data with possibly non-exchangeable groups whose dependencies can be characterized by a known […]
- by Caitlin A MadisonParkinson's disease (PD), characterized by death of dopaminergic neurons in the substantia nigra, is the second most prevalent progressive neurodegenerative […]
- by Erika L Garcia-VillatoroTertiary lymphoid tissues (TLTs) are adaptive immune structures that develop during chronic inflammation and may worsen or lessen disease outcomes […]
- by Roanna A DeblerThe etiology of major depressive disorder (MDD) remains poorly understood. Our previous studies suggest a role for the aryl hydrocarbon […]
- by Gioia HeraviMonounsaturated fatty acids (MUFAs) play a pivotal role in maintaining endoplasmic reticulum (ER) homeostasis, an emerging hallmark of cancer. However, […]
- by Fangting ZhouThe advances of modern sequencing techniques have generated an unprecedented amount of multi-omics data which provide great opportunities to quantitatively […]
- by Madison E EdwardsLipids are important biomarkers within the field of disease diagnostics and can serve as indicators of disease progression and predictors […]