Chapkin Lab is pleased to announce the funding of a new grant!
Attempts to target aberrant Wnt signaling using drugs still face multiple hurdles due to poor tumor cell targeting, negative side effects associated with required long-term treatments and a poor understanding of the mechanisms of action. Consequently, there is an urgent need to further assess non-toxic Wnt targeted therapeutic approaches. This recently funded NIH grant proposal seeks to develop novel membrane targeted therapeutic approaches to abate abnormal Wnt signaling in the colon.