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Precision Exfoliomics

Papers of Interest
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Personalized nutrition using microbial metabolite phenotype to stratify participants and non-invasive host exfoliomics reveal the effects of flaxseed lignan supplementation in a placebo-controlled crossover trial, 2022
Exfoliated epithelial cell transcriptome reflects both small and large intestinal cell signatures in piglets, 2021

Assessing the Multivariate Relationship between the Human Infant Intestinal Exfoliated Cell Transcriptome (Exfoliome) and Microbiome in Response to Diet, 2020

Non-invasive evaluation of the equine gastrointestinal mucosal transcriptome, 2020
 

Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans, 2019
Infant nutrition and the microbiome: Systems biology approaches to uncovering host–microbe interactions, 2017
The non-invasive exfoliated transcriptome (exfoliome) reflects the tissue-level transcriptome in a mouse model of NSAID enteropathy, 2017
Non-invasive analysis of intestinal development in preterm and term infants using RNA-Sequencing, 2014
Noninvasive molecular fingerprinting of host–microbiome interactions in neonates, 2014
A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis, 2012
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response, 2012
Host-microbe interactions in the neonatal intestine: role of human milk oligosaccharides, 2012
A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis1–3, 2011
Noninvasive stool-based detection of infant gastrointestinal development using gene expression profiles from exfoliated epithelial cells, 2010
Mother’s milk:  A rich opportunity, 2010
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach, 2010
Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas, 2009
A two-stage normalization method for partially degraded mRNA microarray data, 2006

 

Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study, 2003
Non-invasive detection of fecal protein kinase C BII and z messenger RNA: putative biomarkers for colon cancer, 1998
Dietary fiber differentially alters cellular fatty acid‐binding protein expression in exfoliated colonocytes during tumor development, 1998
Dietary fat and fiber alter rat colonie protein kinase C isozyme expression, 1995
Noninvasive detection of putative biomarkers for colon cancer using fecal messenger RNA, 1995
Dirty diaper contents may inform researchers of infant intestinal development and disease susceptibility