Major Goals: The goal of this proposal is to determine how environmental factors influence mutualistic host-microbe interactions in a longitudinal, prospective birth cohort of 400 children and to relate those to infant growth trajectory and weight and body composition. For this purpose, we will utilize our novel modeling methodology targeting simultaneous analysis of host-commensal gene expression.
*Status of Support: Active/NCE
Project Number: NIH RO1 DK107561
Name of PD/PI: Donovan/Chapkin
*Source of Support: NIH
*Primary Place of Performance: Texas A&M University, College Station, Texas
Project/Proposal Start and End Date: 6/2017-3/2024
* Total Award Amount (including Indirect Costs): $3,324,204 ($831,190 RSC)